(CNN) -- Tropical Storm Ian threatens another blow to air travel as it moves up the East Coast and away from the Florida panhandle, where airports are assessing conditions and determining when service can safely resume.
"Tropical storm Ian is moving off of Florida into the Atlantic and is expected to turn northwest and make landfall again in the Carolinas tomorrow [Friday]," the Federal Aviation Administration said in a statement, saying passengers should check on the status of their flights with the airlines.
In Florida, a number of airports remained closed on Thursday with hundreds of flight cancellations in the wake of the storm.
Airports starting to reopen
All flights were canceled Thursday at Jacksonville International Airport, which announced that it will reopen on Friday. The TSA checkpoint will open at 7 a.m., the airport said on Twitter. Some airlines may operate reduced schedules, so passengers are advised to check with their airlines.
Orlando International Airport said Thursday afternoon that damage inspections are underway. The airport did not immediately report the nature of any damage discovered during the assessments.
"Due to the extent of the storm, no timeframe has been selected for when MCO will return to normal operations," the airport said.
Melbourne Orlando International Airport -- one of the smaller commercial airports in Florida with service from Allegiant, American and Delta -- said it plans to reopen at 6 a.m. ET Friday.
Tampa International Airport expects "high passenger volumes" when it reopens at 10 a.m. Friday.
CEO Joe Lopano said in a statement that Tampa International is "very lucky to have come out on the other side of this largely unscathed."
Sarasota Bradenton International Airport anticipates reopening by late Friday, CEO Rick Piccolo told CNN. He watched from his office as the storm pulled apart the airport's roof.
"While we won't look as pretty as we used to because the ceiling's all gone, we'll be functional," he said.
St. Pete-Clearwater International plans to reopen Friday morning.
Key West International Airport reopened at 7 a.m. Thursday, the airport said on its website.
More operational updates
The airports below remained closed as of 6 p.m. ET on Thursday:
• Daytona Beach International
• Southwest Florida International (Fort Myers-Lee County) is closed to commercial flights; however, it's open to emergency personnel and humanitarian flights.
Orlando Sanford International Airport is also closed through at least Thursday, according to the airport's website
Travelers are advised to check airport websites and social media postings as well as with their airlines for specific information and to confirm timing.
The following international airports in Florida are open but some flights could be delayed and canceled:
• Fort Lauderdale-Hollywood International
• Miami International
• Palm Beach International
• Northwest Florida Beaches International (Panama City-Bay County)
• Pensacola International
• Tallahassee International
As for smaller airports, hard-hit Punta Gorda is closed through at least Thursday.
CEO James Parish said Punta Gorda Airport experienced "extensive" damage to hangars at the airport and does not have power in the passenger terminal. Once power is restored, Parish said the airport will make plans to restore service from Allegiant Air.
Gainesville Regional is expected to reopen at 8 a.m. Friday.
Roughly 2,050 Thursday flights in the United States had been canceled by 5 p.m. ET, according to data from flight tracking site FlightAware. More than 2,100 US flights were canceled on Wednesday.
The airports in Orlando and Tampa were leading with the most cancellations late Thursday afternoon. More than 1,400 flights scheduled for Friday had also been canceled by 5 p.m. Thursday.
American Airlines says operations at its fourth-largest hub in Miami are recovering.
American customers traveling through airports in Florida, Georgia and the Carolinas can rebook flights without change fees.
Other US carriers, including Delta, Southwest and United, have also introduced flexible policies for impacted passengers.
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